Hui Wang
Harvard University
Department of Molecular and Cellular Biology
Biological Laboratory
16 Divinity Avenue
Cambridge, MA 02138
(617) 495-2646
wang4@fas.harvard.edu

Ph.D. in Chemistry, New York University.
     Advisor: Dr. Nadrian C. Seeman.
     Thesis: Construction and Application of Single-Stranded Nucleic Acid Knots
B.A. in Chemistry, New York University.

Research Associate at Harvard University, 1999-Present
Research Associate at The Scripps Research Institute, 1997-1999.
Research Associate at New York University, 1996-1997.
Graduate Research Fellow at New York University 1992-1996.
Graduate Teaching Fellow at New York University 1990-1992.

Research Papers

H. Wang, M.N. Griffiths, D.R. Burton, & P. Ghazal. "Rapid Antibody
Responses by Low-Dose, Single-Step, Dendritic Cell-Targeted Immunization."
Proceedings of the National Academy of Sciences, USA. 96, 847-852 (2000).

X.J. Li, H. Wang & N.C. Seeman. "Direct Evidence for Holliday Junction
Crossover Isomerization." Biochemistry. 36, 4240-4247 (1997).

F. Liu, H.Wang & N.C. Seeman. "Short Extensions to Sticky Ends for DNA
Nanotechnology and DNA-based Computation" Nanobiology, 4, 257-262 (1997).

H. Wang, R.J. Di Gate & N.C. Seeman. "An RNA Topoisomerase."
Proceedings of the National Academy of Sciences, USA. 93, 9477-9482
(1996).

H. Wang & N.C. Seeman. "Structural Domains of DNA Mesojunctions."
Biochemistry. 34, 920-929 (1995).

S.M. Du, H. Wang, Y-C. Tse-Dinh & N.C. Seeman. "Topological
Transformations of Synthetic DNA Knots." Biochemistry. 34, 673-682
(1995).

H. Wang, S.M. Du & N.C. Seeman. "Tight Single-Stranded DNA Knots."
Journal of Biomolecular Structure & Dynamics. 10, 853-863 (1993).

Reviews

H. Wang and D. Branton. "Nanopores with a spark for single-molecule detection."
Nature Biotechnology 19, 622-623 (2001).

N.C. Seeman, H. Wang, X. Yang, F. Liu, C. Mao, W. Sun, L. Wenzler, Z.
Shen, R. Sha, H. Yan, M.H. Wong, P. Sa-Ardyen, B. Liu, H. Qiu, X. Li, J.
Qi, S.M. Du, Y. Zhang, J.E. Mueller, T.-J. Fu, Y. Wang, and J. Chen, "New
Motifs in DNA Nanotechnology", Nanotechnology 9, 257-273 (1998).

N.C. Seeman, J. Chen, S.M. Du, J.E. Mueller, Y. Zhang, T.-Ju Fu, Y.
Wang, H.Wang & S. Zhang. "Synthetic DNA Knots and Catenanes." New
Journal of Chemistry. 17, 793-755 (1993).

Proceedings/Book Chapters

H. Wang, R.J. Di Gate and N.C. Seeman, E. coli DNA "The Construction of
an RNA Knot and its Role in Demonstrating that Topoisomerase III is an RNA
Topoisomerase." Structure, Motion, Interaction and Expression of
Biological Macromolecules, ed by R.H. Sarma and M.H. Sarma, Adenine Press,
New York, pp. 103-116 (1998).

N.C. Seeman, J. Chen, Y. Zhang, B. Liu, H. Qiu, T.-J. Fu, Y. Wang, X.
Li, X. Yang, J. Qi, F. Liu, L.A. Wenzler, S, Du, J.E. Mueller, H. Wang, C.
Mao, W. Sun, Z. Shen, M.H. Wong, H, Yan and R. Sha, "A Bottom-Up Approach
to Nanotechnology Using DNA", In: Biological Molecules in Nanotechnology,
ed. by S.C. Lee, IBC Libraries, Southborough, MA, Chapter 8 (1998).

N.C. Seeman, H. Wang, B. Liu, J. Qi, X. Li, X. Yang, F. Liu, W. Sun, Z.
Shen, Y. Wang, R. Sha, C. Mao, S. Zhang, T.-J. Fu, S. M. Du, J.E. Mueller,
Y. Zhang and J. Chen, "The Perils of Polynucleotides: The Experimental Gap
Between the Design and Assembly of Unusual DNA Structures", In: DNA Based
Computers II, ed.by L.F. Landweber and E.B. Baum, Am. Math. Soc.,
Providence, pp. 215-233 (1998).

N.C. Seeman, H. Wang, J. Qi., X.J. Li, X.P. Yang, Y. Wang, H. Qiu, B.
Liu, Z. Shen, W. Sun, F. Liu, J.J. Molenda, S.M. Du, J. Chen, J.E.
Mueller., Y.Zhang, T.-J. Fu, and S. Zhang, "DNA Nanotechnology and Topology". In:
Biological Structure and Dyinamics, ed. by R.H. Sarma and M.H. Sarma,
Adenine Press, New York, vol. 2, pp. 319-341 (1996)

N.C. Seeman, Y. Zhang, S.M. Du, H. Wang, J.E. Mueller, Y. Wang, B. Liu,
J.Qi and J. Chen, "The Control of DNA Structure and Topology: An Overview".
Molecularly Designed Ultrafine/Nanostructured Materials: Materials
Research Society Symposium Proceedings 351 57-66 (1994).

Abstracts

H. Wang, R.J. Di Gate & N.C. Seeman. "E. coli DNA Topoisomerase III is
an RNA Topoisomerase." Tenth Conversation: Biomolecular Stereodynamics,
June 1997. Albany, New York.

H. Wang, R.J. Di Gate & N.C. Seeman. "An RNA Topoisomerase." 41st
Annual Meeting of the Biophysical Society, March 1997, New Orleans,
Louisiana.

H. Wang & N.C. Seeman. "Structural Domains of DNA Mesojunctions."
Ninth Conversation: Biomolecular Stereodynamics, June 1995. Albany, New
York. Abstract # a253.

H. Wang, S.M. Du & N.C. Seeman. "Tight Single-Stranded DNA Knots."
Eighth Conversation: Biomolecular Stereodynamics, June 1993. Albany, New
York. Abstract # a174.

Oral Presentation

"An RNA Topoisomerase." Tenth Conversation: Biomolecular Stereodynamics,
June 1997. Albany, New York.