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2007 Undergraduate Biochemical Sciences Honors Theses 

Leah J. Blank
Transcription Factor Networks and Signaling: A Molecular Analysis of Lung Development
Dr. Doug Melton, Laboratory Sponsor

Resmi  Ann Charalel
Towards Genome Engineering and Recoding the Escherichia Coli Genome
Dr. George Church, Laboratory Sponsor

Nancy Chen
Genomics and population Genetics of I-regulatory regions of House Finch (Carpodacus mexicanus) immune system genes during an epizootic
Dr. Scott Edwards, Laboratory Sponsor

Yicheng Chen
The Role of Endocytosis in Granule Cell Migration
Dr. Rosalind Segal, Laboratory Sponsor

Christine Elise Cherella
Characterization of Phospho-specific IRS1 Monoclonal Antibodies - Initial studies of IRS1 S265 and S1135 phosphorylation
Dr. Morris White, Laboratory Sponsor

Juliet Girard
Detecting tension between sister centromeres plays a role in the spindle checkpoint in budding yeast
Dr. Andrew Murray, Laboratory Sponsor

Wei He
The Role of Mutations in B-tubulin Isotype III in the Clinical Disorder Congenital Fibrosis of the Extraocular Muscle III
Dr. Elizabeth Engle, Laboratory Sponsor

Brian Thomas Ho
Chromosome mobility varies throughout the Escherichia coli cell cycle: A study in bacterial Chromosome dynamics
Dr. Nancy Kleckner, Laboratory Sponsor

Victoria T. Ho
Expression and Function of Bone Morphogenetic Protein 3 in Chick Embryonic Development
Dr. Vicki Rosen, Laboratory Sponsor

Sinisa Hrvatin
High throughput screening and isolation of natural product biosynthetic gene clusters
Dr. Christopher Walsh, Laboratory Sponsor

Robert Jeffrey Huang
Structural Studies of the Ankyrin Repeats of TRPV Ion Channels
Dr. Rachelle Gaudet, Laboratory Sponsor

Hala Asfand Iqbal
The Role of Major and Variant Histones in Drosophila Development
Dr. Ahmad Kami, Laboratory Sponsor

Pimkwan Jaru-ampornpan
Partial protection of clinically SIV-infected rhesus monkeys against a heterologuous mucosal challenge
Dr. Norman Letvin, Laboratory Sponsor

Pichamol Jirapinyo
Polysaccharide A on the surface of Bacteroides fragilis induces TH1 subtype differentiation through activation of the transcription factors T-box expressed in T cells (T-bet)
Dr. Dennis Kasper, Laboratory Sponsor

Kevin Koo
Ethanol-Induced Microphthalmia in the Developing Zebrafish Retina
Dr. John Dowling, Laboratory Sponsor

Luisa Lara
The Role of C-type Lectins in Caenorhabditis elegans Immunity
Dr. Dennis Kasper, Laboratory Sponsor

Daniel Junseung Lee
Retrograde axonal transport and motor neuron function
Dr. Rosalind Segal, Laboratory Sponsor

Hana Lee
Array-based high-resolution genotyping of recombinant inbred lines for quantitative trait loci analysis
Dr. Christine Queitsch, Laboratory Sponsor

Deepali Malhorta
Biochemical Studies of the DnaA Protein from Thermus Thermophilus
Dr. David Jeruzalmi, Laboratory Sponsor

Ryan McCaffrey
A Link Between the Fanconi Anemia Pathway and Translesion DNA Synthesis
Dr. Alan D’Andrea, Laboratory Sponsor

Kristen Mengwasser
Mechanism of Drug Resistance Acquired by EGFR T790M Mutation
Dr. Michael Eck, Laboratory Sponsor

Alissa Anne Mueller
I.  Structural and Mechanistic Studies of TadA, an Adenosine Deaminase that Acts on tRNA  
II.  Structural and Biochemical Analysis of the C-terminal Domain of UvrC, A DNA Damage Repair Enzyme
Dr. Greg Verdine, Laboratory Sponsor

Mei Rosa Ng
Microenvironmental Regulators of Microtubules in Cardiac Myocytes
Dr. Kit Kevin Parker and David Weitz, Laboratory Sponsors

Thomas R. Noriega
Fatty acid-derived membrane lipids regulate the SREBP pathway through positive feedback
Dr. Axel Nohtrufft, Laboratory Sponsor

Michael Jeffrey Podolsky
The Role of Activity in the Formation of Odor Maps
Dr. Venkatesh Murthy, Laboratory Sponsor

Sutheera Ratanasirintrawoot
The contribution of notch signaling to neural crest development in the zebrafish model of melanoma
Dr. Leonard Zon, Laboratory Sponsor

Jennifer Rood
Promoter Structure and Function in the Transcriptional Network Activated by the MAP Kinase Hog1
Dr. Erin O’Shea, Laboratory Sponsor

Julia Rotow
Aspects of Gene Regulation in the óK Regulon During Sporulation in Bacillus subtilis
Dr. Rich Losick, Laboratory Sponsor

Hersh Sagreiya
An Investigation of the Mechanisms Involved in the Footsteps, Kickback, Wenceslas, and Belly Dancer Illusions
Dr. Margaret Livingstone, Laboratory Sponsor

Rajan Anthony Sonik
The Role of the Human and Mouse Erythroid AE1 N-terminal Cytoplasmic Domain in Binding Glycophorin A
Dr. Seth Alper, Laboratory Sponsor

Vasanthi Sridhar
Analysis of the Role of the Non-Receptor Tyrosine Kinase Family in Drosophila Embryo Axon Guidance
Dr. David Van Vactor, Laboratory Sponsor

David Staudt
The Requirement for Embryonic Stem Cell Chromatin in Fusion-Mediated Nuclear Reprogramming
Dr. Kevin Eggan, Laboratory Sponsor

Michael Swita
2C7-Protamine Fusion Protein as a Novel siRNA Delivery System for HIV Therapy
Dr. Judy Lieberman, Laboratory Sponsor

Aileen Sy
Embryonic Pancreatic Progenitors Replicate Homogeneously to Produce the Mature Adult Pancreas
Dr. Doug Melton, Laboratory Sponsor

Shyam K. Tanguturi
Identification of Novel Regulators of Globin Expression for the Treatment of Sickle Cell Disease and Thalassemias
Dr. Todd Golub, Laboratory Sponsor

David Thaisrivongs
Synthesis of the C5’-C2 and C36-C48 Subunits of Aflastatin A
Dr. David Evans, Laboratory Sponsor

Benjamin Tseng
Transcriptional Regulation of Members of the Tripartite Motif Family in Response to Viral Infection
Dr. Tom Maniatis, Laboratory Sponsor

Nadia Wan
Studies on the immunogenicity, carbohydrate specificity, and conformational changes of the rotavirus VP8*core
Dr. Philip Dormitzer, Laboratory Sponsor

Michael Dale Wang
Building on the First Generation of Accurate Massively Parallel Multiplex Sequencing
Dr. George Church, Laboratory Sponsor

Sophia Wang
An investigation into the fighting behavior of Drosophila melanogaster using rutabaga and amnesiac memory mutants.
Dr. David Kravitz, Laboratory Sponsor

Alvin Wong
Molecular Effectors of Angiogenesis: The Role of Cyclophilin B in the Angiogenic Switch
Dr. Moses Marsha, Laboratory Sponsor

Albert Wu
Sequential molecular analysis of tumor stroma in a spontaneous tumor model
Dr. David Scadden, Laboratory Sponsor

Vijay Yanamadala
A Novel Ga12-Mediated Apoptosis Pathway and its Potential Role in the Development of Polycystic Kidney Disease
Dr. Brad Denker, Laboratory Sponsor

Nicolas A. Yannuzzi
Models of Muller Glial Cell Disruption and the Consequences on Retinal Health and Visual Function in the Zebrafish Retina
Dr. John Dowling, Laboratory Sponsor

Dongbo Yu
Functional expression screens with luciferase- and GFP-based reporters to probe NFAT/FoxP3 and PI3 kinase signaling networks
Dr. Brian Seed, Laboratory Sponsor

Yi-Chen Lilly Zhang
NFAT1 Induces a Transcriptional Program of T Cell Anergy that is Functionally Distinct from Regulatory T Cell Suppression
Dr. Anjana Rao, Laboratory Sponsor

Advising Notes:

Head Tutors' Notes for students who entered before Sept 05
Head Tutors' Notes for students who entered Sept 05
Course Sequences for students who entered before Sept 05
Course Sequences for students who entered Sept 05
Physical Chemistry Requirement
Genetics Requirement
Intermediate and Advanced Courses
Tutorial
Honors

     Research Opportunities:

91r and 99 (Courses)
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Henderson Prize
Board of Tutors in Biochemical Sciences
2007 Theses
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2005 Theses