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2005 Undergraduate Biochemical Sciences Honors Theses 

Jonathan Abraham
Development of Ebola Zaire GP2 Variants for Inhibitor Design Studies
Dr. Stephen C. Harrison, Laboratory Sponsor

Joshua Adam Albrecht
V(D)J Joining in Saccharomyces Cerevisiae
Dr. Marjorie Oettinger, Laboratory Sponsor

Krishna G. Aragam
Matrix Metalloproteinases Provide a Caspase-1-Independent Mechanism For Interleukin-18 Activation
Dr. Peter Libby, Laboratory Sponsor

Jessica Bazick
The effect of HIV-1 glycoprotein 160 mutations on cell fusion and infectivity
Dr. Joseph Sodroski, Laboratory Sponsor

Katherine Cembrola
Regulation of Dendritic Cell CD1 Expression by Self Lipids
Dr. Michael B. Brenner, Laboratory Sponsor

Christopher R. Clearfield
A Quantitative Analysis of Cell-Cycle Timing in Budding Yeast
Dr. Andrew Murray, Laboratory Sponsor

Allison M. Colbert
The role of the CART gene (Cocaine and Amphetamine Regulated Transcript) in neovascular age-related macular degeneration, using an Extremely Discordant Sib-Pair study design
Dr. Margaret DeAngelis, Laboratory Sponsor

Ishani Ganguli
Single Nucleotide Polymorphisms in Plasmodium vivax Apical Membrane Antigen-1 from Sri Lankan Isolates Show Evidence of Host Selection Pressure
Dr. Dyann Wirth, Laboratory Sponsor

Michael D. George
The Importance of the Polyomavirus T Antigens in the Regulation of Viral Chromatin Modifications
Dr. Thomas L. Benjamin, Laboratory Sponsor

Sarah J. Hill
Characterization of a Novel Chromodomain Protein
Dr. David Livingston, Laboratory Sponsor

Tammy T. Hshieh
Quantitation of ApoE Domain Interactions in Alzheimer Disease Brain: Conformational Differences in APOE-ε3/3, APOE-ε4/4 Genotypes
Dr. Bradley T. Hyman, Laboratory Sponsor

Honor Hsin
Toward the Molecular Architecture of Neural Circuits Mediating Innate Aggressive Behavior in the Mammalian Brain
Dr. Catherine Dulac, Laboratory Sponsor

Crystal Hung
Positional cloning of rad-2, a member of an embryonic C. elegans DNA damage-induced checkpoint bypass pathway
Dr. W. Matthew Michael, Laboratory Sponsor

Scott L. Jones
FRET reveals the dominant form of CD39 to be a monomer in living cells
Dr. Guido Guidotti, Laboratory Sponsor

Jiyeon Kim
The Effects of Notch Signaling on the Chromatin State of Hematopoietic Stem Cells
Dr. Nadia Carlesso, Laboratory Sponsor

Fang S. Ko
Pax6 expression and lens development are regulated by Sox genes
Dr. Richard Maas, Laboratory Sponsor

Evgeniy Kreydin
Role of the Chemical Chaperone Trehalose in the Near-freezing Stress Response of S. cerevisiae
Dr. Alfred L. Goldberg, Laboratory Sponsor

Cambrian Liu
Role of Transcription Factor NF-„{B in Synaptic Plasticity    
Dr. Venkatesh Murthy, Laboratory Sponsor

Kimberley S. Mak
Function of the Transcription Factors Dlx1 and Dlx2 in the Development of Schwann Cells from the Neural Crest 
Dr. Charles D. Stiles, Laboratory Sponsor

Caitlin Matson
Mechanisms for Regulation of Novel Demethylase LSD1
Dr. Yang Shi, Laboratory Sponsor

Natalia Mendoza
Identification of an N-terminal Region That May Mediate Intra- and Intermolecular Interaction in the MAPK Scaffold Protein Ste5: Evidence of a Possible RING-H2 Binding Domain     
Dr. Elaine A. Elion, Laboratory Sponsor

Vinod E. Nambudiri
Statins Exert Endothelial Atheroprotective Effects Via the KLF2 Transcription Factor
Dr. Guillermo García-Cardeña, Laboratory Sponsor

Melanie Napier
Identification of Novel Mouse Cytomegalovirus (MCMV) Immune Evasion Genes
Dr. Hidde L. Ploegh, Laboratory Sponsor

Onyinye Diane Offor
Mapping a novel translocation t(X,21) (q26;q22) in a patient with acute myeloid leukemia
Dr. Cynthia Morton, Laboratory Sponsor

Anthony Onah
A Neural Switch Controlling Phototactic Behavior in Drosophila
Dr. Samuel Kunes, Laboratory Sponsor

Do H. Park
Interspecies Variation and Subcellular Localization of Retroviral Restriction Factor TRIM5α
Dr. Joseph Sodrosk , Laboratory Sponsor

Piotr P. Pilarski
The Specificity of HCMV Immunoevasins for Class I versus Class II MHC Molecules and their Preference for Allelic Products of Class I MHC Loci
Dr. Hidde L. Ploegh, Laboratory Sponsor

Evan Rachlin
Recombinant Molecules For Structural And Functional Studies Of The Initiation of DNA Replication In Bacteria
Dr. David Jeruzalmi, Laboratory Sponsor

Diana E. Saville
Characterization of HS5-1, a putative insulator and cis-regulatory element of the α-Protocadherins gene cluster
Dr. Tom Maniatis, Laboratory Sponsor

David Antonio Solá-Del Valle
Structure-function studies of TRPA1, a thermo- and mechano-sensitive ion channel
Dr. Rachelle Gaudet, Laboratory Sponsor

Mona Stoicescu
Investigating the role of Pmd1 and Mds3 in the S. cerevisiae mating pathway
Dr. Elaine A. Elion, Laboratory Sponsor

Yan Xuan
Analysis of SUMO residues and interactions important for repression of Sp3 activity
Dr. Grace Gill, Laboratory Sponsor

Jessica Zhou
Genome-Wide Expression Profiling of Human Blood Reveals Biomarkers for Huntington’s Disease
Dr. Dimitri Krainc, Laboratory Sponsor

Advising Notes:

Head Tutors' Notes for students who entered before Sept 05
Head Tutors' Notes for students who entered Sept 05
Course Sequences for students who entered before Sept 05
Course Sequences for students who entered Sept 05
Physical Chemistry Requirement
Genetics Requirement
Intermediate and Advanced Courses
Tutorial
Honors

     Research Opportunities:

91r and 99 (Courses)
91r Forms
Honors Thesis Proposal Guidelines
Honors Thesis Preparation
Henderson Prize
Board of Tutors in Biochemical Sciences
2007 Theses
2006 Theses
2005 Theses